邢唷??>? FH?E欹?q` 鳵?"2bjbjqPqP5<::b??j?& & & 8^ <?>?<???????????????$?h6h?]!??!!????Laaa!????a!?aa???? 0R虏?& 4?m\b0??,?5???????= ha?T?(?????Q????!!!!>>>?" >>>" *$Nf 燪胈舥€-N*g蕥璭剉謡?\舥蔛vQqSi栢V }6R臽礠孴剺T \gf 穅蔕 ?T:_ B€蛜s^ 4T Vga _] R\ga Th顢 H柟e 4Tf[` l??u 0Xd亯0 顅剉 哊銐燪胈舥€-N*g蕥璭剉謡?\舥剉裇u臽礠0vQ燪胈舥qSi栢V }6R臽礠錘蔛購汵€(W@埿復扂^/gT剉?g剺T0筫誰 愰bDESIREDrug-Eluting Stent Impact on REvascularization penc揯-ND崣e孾te剉€剉舥婳D崣e蹚L?R恎 哊銐€剉4N奮yr乢0v梙V榌_c砙孴qSi栢V }6R臽礠錘蔛?g剺T觺済0觺済 (WDESIRE鑜孮剉3763婳@埿復扂^/gT剉燪胈舥€-N 3683婳€D崣e孾te0vQ-N721婳19.9 €eQb桍e騗nx蕥謡?\舥 鍿 g303婳10.2% 鄀謡?\舥騍剉€(Wdk!kOOb桍e@堉|4ls^貧嶯謡?\舥蕥璭h芉 貜 g722婳24.4% €zzy丂堉|譙_c0謡鉔"?_8^剉€`S,g膥燪胈舥€剉47.4%0*g蕥璭剉謡?\舥€eQb桍e燪胈舥剉qSi栢V }6Rg頬 6e)婼SBP e"140mmHg€`S46.2% NO芠佀唥v苺鶹噾LDL-C e"2.6m m ol/L€`S59.4% S_MR8T遬€`S48.8% GW>fW勜殠NvQ諲3膥€PfW勜殠N@堉|ck8^膥€34.0% P0.0001 0@?n寑P?ls^>132m m o/L€(W*g蕥璭剉謡?\舥膥g貧 緩8.7% >fW勜殠NvQ諲3膥€P0.0001 0,g膥D崣e-N 80.6%剉€譙哊彇繈 s^GW彇繈30.0?12.1 *Ng *g蕥璭剉謡?\舥€;`{k噑5.7% >fW勜殠Nnx蕥剉謡?\舥€4.3% 孴^椫|?\舥€P0.01  ;N亯胈丂垺{ No倠N鯪MACCE 剉裇u噑13.9% Nnx蕥剉謡?\舥€褟14.3%  >fW勜殠N^椫|?\舥€P0.01 0觺簨 燪胈舥€-N謡?\舥裇u噑貧 vQ-N NRKNN珗o蕥 購汵*g蕥璭剉謡?\舥€v梙V榌_c砙蛻0qSi栢V }6R頬 @埿復扂^/gT?g剺T頬0 0sQ.曂?0*g蕥璭剉謡?\舥燪胈舥qSi栢V }剺T Prevalence of unrecognized diabetes and risk factor control among patients with coronary heart disease and prognosis thereof DU Xin, KANG Jun-ping, L?Qiang, NIE Shao-ping, WU Jia-hui, ZHANG Yin, LIU Xiao-hui, L?Shu-zheng, CHEN Fang, WU Xue-si, MA Chang-sheng. Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China Corresponding author: Ma Chang-sheng, E-mail: chshma@vip.sina.com 0Abstract0 Objective To evaluate the prevalence of unrecognized diabetes in patients with coronary heart disease, the control of the risk factors of CHD, and the long-term prognosis of these patients. Methods The clinical data of CHD patients with complete data, including clinical characters, target organ damage, percentage of controlled risk factors, and clinical results during follow up in the DESIREDrug-Eluting Stent Impact on REvascularization database were analyzed. Results 3763 patients after revascularization for coronary heart disease were registered in the DESIRE database, 3683 of which had complete data recorded. 721 of the 3683 patients (19.8%) had established diabetes at admission, 303 (10.2%) without history of diabetes had fast glucose higher than the diagnostic criteria of diabetes. Another 722 patients had impaired fast glucose (IFG). 47.4% of the 3683 CHD patients had impaired glucose metabolism. The prevalence rates of systolic blood pressure e"140 mmHg, low density lipoprotein cholesterol e"100 mg/dL, and current smoker at admission were 46.2%, 59.4%, and 48.8% respectively, all significantly higher than those of the established diabetes patients and those without (P =0.05, 0.0001, and 0.0001 re6P`h???   " 0 2 < > P T ??8 : X Z ??????????????    T V h l ??NP^b蜴苕茯茯苄苄苄苄苄茯芷苕苕烘烘栖埽墉埽埽軏軏茯?h ??hZe6乤Jo(h ??h?0KHaJo(h ??h?0aJo(h ??hZe6乚乤Jo(h ??h ?KHaJo(h ??h ?aJo(h ??hZe>*aJo(h ??hZeaJo(h ??hZeKHaJo(h ??hZe5乗乤Jo(56??F??????????????2?????????????????????dh ?WD`?gd ?? ?WD`?gd ??gd ?? ?WD`?gd ?? ?WD`?gd ??$a$gd ??gd?W? 22N\r~€??????????? !"9E_`mp(,2BL? &6FZ?蹼揠揠揠揠针呻呻坎氩瞸s|s|l|l|l| hlm?aJo(h ??hZeaJh ??hZeaJo(h?hlm?6乤Jo(&h?hlm?6丱JPJQJ^JaJo(h?hZe6乤Jo(h ??hZe5乗乤Jo(h?O5乗乤Jo(h ??hg?5乗乤Jhg?5乗乤Jh ??hg?5乗乤Jo(hg?5乗乤Jo(h?:5乗乤Jo(*?????????*:Nx|??024<>LNXZlp??????????.579<@[^ck蜩嶷徼阼谚世防世世瑭濊濊濊濊濊╄谚掩钁堣谚谚佽佽谚 hy{?aJo(h ??hoG?aJh ??hoG?5乗乤Jh ??hZe>*aJo(h ??hZeaJmH o(sH h ??hA]?aJh ??hA]?aJo( hA]?aJo(h ??hZeaJ h??aJo( h??aJo(h ??hZeaJo(h ??hZe5乗乤Jo(2?[alpty???? F\^`fhrt??? Hb??????????&&$&J&V&?????'孱揞念屮母腐腐腐腐腐睥顩顩顧顠铄顙罡顙 h?CaJo( h??aJo(U h?aJo(h ??hZe6乚乤Jo(hy{?KHaJo(h ??hZeKHaJo(h ??hZeKHaJmH o(sH h ??hy{?aJo( h滶aJo(h ??hZeaJh ??hZeaJo( hy{?aJo(6spectively). The prevalence of three vessel disease was 41.6%, similar to that of the established diabetic patients (45.7%), and significantly higher than that of those without diabetic (P0.0001). The percentage of creatinine>132 mmo/L signifying impaired renal function was 8.7% in the patients with unrecognized diabetes, significantly higher than those of the other 3 groups (all P0.0001). 80.6% patients were followed up for a mean time of 30.0?12.1 months. The mortality rate of the patients with unrecognized diabetes was 5.7%, significantly higher than those of the patients with established diabetes (4.3%), those with IFG (3.6%), and those without diabetes (2.3%, all P0.01). The rate of major adverse cardiac and cerebral events of the patients with unrecognized diabetes was 13.9%, similar to that of patients with established diabetes (14.3%), and significantly higher than that of the patients without diabetes (10.0%, P0.01). Conclusion The prevalence rate of diabetes is high in the CHD patients, the diagnosis of one third of which is missed. The target organ damages are more common and the risk factors control is poor among these patients. The prognosis of unrecognized patients after revascularization is poor in comparison with other groups. 0Key words0Unrecognized diabetes; Coronary heart disease; Risk factors; Prognosis     \O€USMO枡龕;S褃'Yf[D朸\S琋塠?Sb柮_匭褃 100029 惎媆O€l??u E-mail:  HYPERLINK "mailto:chshma@vip.sina.com" chshma@vip.sina.com, T€鹼5u輯13901357404l??u  13910884181T:_  ,g槝譙973R槝D崺R 槝鱏2003CB517103 'B'b't'x'z'?????????$(*(:(^(???)))R)X)???????**&*.*2*\*??????+ +(+4+8+:+箨筻余搪潭绿嗵嗵嗵嗵訜嗵酂鄸搪搪虌绿嗵筇嗵偺嗵箨?h滶OJQJo(h?CaJmH o(sH h ??hZeaJh ??hZeaJmH o(sH hoG?KHaJo(h ??h?CKHaJo(h ??h?CaJo( h?CaJo(h ??hZe6乚乤Jo(h ??hZeaJo(h?CKHaJo(h ??hZeKHaJo(3:+<+F+H+P+R+T+V+d+~+??,.,8,~,????0-<-@-B-D-R-T-d-x-z-??????????.躅珙巯刘乎喊┌酴酴潝濙﹫鮷鮰鮰鮰鮰鮰mg h黫aJ h?aJo( h發=aJo(h ??hZe5乗乤Jo(hDtihZe6乤Jo(hDtiKHaJo(h ??hZeKHaJo( hDtiaJo(h ??hDtiaJo( h?aJo(h ??hZeaJmH o(sH h?ChZe6乤Jo(h?Ch?C6乤Jo( h黫aJo( h?CaJo(h ??hZeaJo((.0.@.B.L.T.\.????????????? 00.0@0B0L0N0Z0h0j0?????????? 1141Z1^1`1b1??22 2"2黢玎玎玎玎玎玎玎缭如噻苦苦跨噻勃ΚΚΚΑˇ柂彧ˇ嫴hy{? h滶0Jo(?jh滶U h滶o(h滶jh滶Uh ??hZe5乗乤Jo(h ??hZeaJh?hZe5乤Jo(h?h?5乤Jo( h?aJo(h ??hZeaJo( h黫aJh ??h黫aJ422 2"2??? ?WD`?gd ??3 01?2P皞. 捌A!癟"昂#悹$悹%?癝班 惄?D猩陏?寕?K?chshma@vip.sina.com嗌陏?寕?K?6mailto:chshma@vip.sina.com??N@?N ck噀 $1$a$$CJKHPJ_HaJmH nHsH tH$A@??$ 貫祂=刉[SOFi@??F nf恏?h :V ?4?4? la? k@?? 鄀Rh? <B@?< ck噀噀,g$7$8$H$a$KHaJLC@L ck噀噀,g)蹚$?7$8$H$WD`?a$KHaJPP@P ck噀噀,g 2$7$8$H$a$CJKHOJaJmHsHN@"N u?w'$ ?9r &dG$P?a$CJaJ< @2< u??$ ?9r G$a$CJaJ*U@?A* 厤 >*B*ph*'<&!"&?!"&??*KCr?Fan??+t"?t"?t"Hd3t"?t"e#t"?t"y揔t"?t"?t"O?t"O?t"O?t" CCr?Fabdeghjkmn??'(+?0€€?0€€?€€?€€?0€€?0€€?€€?€€?€€?0€€€?0€€€?0€€€?0€€€?0€€€?0€€€?0€€€?0€€€?0€€?0€€?0€€?0€€?0€€€?0€€Cr?F+K?008 ?K?00€K?00€0I?00€?0€€?0€€?0€€ ???':+."2 2"2 2=g{?X€??@?€€€?饞??? ? ?養 ?S ??? ?? u?瑩?v?tWP t秧Q 许R ,?T 詟OU dNKW ゐ?X寣Y ???`????????+ ?d??????+ V&*€urn:schemas-microsoft-com:office:smarttags€place€http://www.5iantlavalamp.com/h%*€urn:schemas-microsoft-com:office:smarttags€City0€http://www.5iamas-microsoft-com:office:smarttagsZ!*€urn:schemas-microsoft-com:office:smarttags €PlaceName€http://www.5iantlavalamp.com/Z *€urn:schemas-microsoft-com:office:smarttags €PlaceType€http://www.5iantlavalamp.com/_*€urn:schemas-microsoft-com:office:smarttags€country-region€http://www.5iantlavalamp.com/< $*€urn:schemas-microsoft-com:office:smarttags€chmetcnv€ ?y €0€1€132€2.6€False€HasSpace€m€Negative €NumberType €SourceValue€TCSC€UnitName       "$%(),-/03478:;>?BCGHJK?????????????'7:<B`cek????????????? $)6<INOPQX_????????? '().13qr?FGOP  ??bn????? +!\]??b+:zzb??+b+gm?訲迡劋刓???^劋`刓?.?凥刓??H^凥`刓?)?勳刓???^勳`刓?.?剱刓???^剱`刓?.??刓??4^?`刓?)?勜 刓???^勜 `刓?.?剕 刓??| ^剕 `刓?.?? 刓?? ^? `刓?)?勀刓???^勀`刓?.gm?          ??滶黫??0?:發=?C\G?O汫U?WZeDti?j????/???oG?y{?? ? ????g?A]??lm??? C?abdgjm??+QaQaQaQaQa@€aa杼F$aa`鶫XFFF  *pp @ppp,@pp&UnknownG?噝 €Times New Roman5?€Symbol3&? 噝 €ArialI&?? ??Arial Unicode MS;??媅SOSimSun q??h0-害?浩6元?>K K !-!),.:;?]}????    & 6"0000 0 0 00000  =@\]^?([{?  0 0 00000;[??T???個2d[[?? 3僸?HX(??? ?2燪胈舥€-N*g蕥璭剉謡?\舥蔛vQqSi栢V }6R臽礠孴剺T ju儽傢V ?鄥燆鵒h珣+'迟0??????? $0 P \ h t€????8冠心病患者中未诊断的糖尿病及其危险因素控制情况和预后  Normal.dot 番茄花园20Microsoft Office Word@鬔?@腣G茗?@李鮉?@hǒ?K ?胀諟.摋+,D胀諟.摋+,?? X`lt|? ????? [? ? 8@ _PID_HLINKS?Apqmailto:chshma@vip.sina.com ? !"#$%&?()*+,-./01234?6789:;<?>?@ABCD??G???Root Entry ?F甬撞?I€Data 1Table'?WordDocument5<SummaryInformation(5DocumentSummaryInformation8=CompObjm??  ?FMicrosoft Office Word 文档 MSWordDocWord.Document.8?瞦